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To reduce the risk of cardiovascular issues in adults with type 2 diabetes

Semaglutide (Wegovy/Ozempic) is an FDA-approved GLP-1 receptor agonist used weekly to support weight loss

This controversy encompasses several critical aspects, including regulatory approval and off-label use, the balance of efficacy versus potential risks, cost and accessibility, equity in resource allocation, and the broader implications of medicalizing obesity

In addition, we performed stratified analyses by obesity status among participants with diabetes to assess whether obesity modified the association between GLP-1RA exposure and SUD risk

The medication's real-world effectiveness transformed obesity medicine outcomes